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CD11b expression correlates with monosomal karyotype and predicts an extremely poor prognosis in cytogenetically unfavorable acute myeloid leukemia

โœ Scribed by Chen, Mei-Hsi; Atenafu, Eshetu; Craddock, Kenneth J.; Brandwein, Joseph; Chang, Hong


Book ID
122568047
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
766 KB
Volume
37
Category
Article
ISSN
0145-2126

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โœ Hong Chang; Joanna Yeung; Joseph Brandwein; Qi-long Yi ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 215 KB

AML patients with normal karyotype comprise the largest subgroup (โˆผ50%) but have a highly heterogeneous clinical course. By multiparameter flow cytometry we analyzed CD7 expression along with other phenotypic markers in 185 patients with normal-karyotype AML. CD7 was expressed in 68 (37%) patients.