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CD103 Manipulation Leads to T Regulatory Cells Upregulation

โœ Scribed by N. Zikri; E. Schumer; J. Wang; A.A. Gaughan; G.A. Hadley; S.D. Moffatt-Bruce


Book ID
116706218
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
44 KB
Volume
158
Category
Article
ISSN
0022-4804

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Regulatory T cells (Treg) mediate tolerance towards self-antigens by suppression of innate and adaptive immunity. In cancer patients, tumor-infiltrating FoxP31 Treg suppress local anti-tumor immune responses and are often associated with poor prognosis. Markers that are selectively expressed on tumo