CD10+ stromal cells in fibroadenomas and phyllodes tumors of the breast
β Scribed by M. Zamecnik; Z. Kinkor; A. Chlumska
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 179 KB
- Volume
- 448
- Category
- Article
- ISSN
- 1432-2307
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Short-term cultures of 50 fibroadenomas of the breast were cytogenetically analyzed. Nine tumors were found to display clonal chromosome aberrations. One had multiple, cytogenetically unrelated clones, whereas the others had a single abnormal clone each. Four cases had one balanced translocation as
## Abstract In adult mammals, early Bβlymphopoiesis takes place in the bone marrow in close association with stromal cells. Both the phenotype of the stromal cells and the molecules involved in this essential interaction are as yet inadequately described. In this study, all benign, differentiating