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CD-ring modified vitamin D3 analogs and their superagonistic action

✍ Scribed by Guy Eelen; Lieve Verlinden; Roger Bouillon; Pierre De Clercq; Alberto Muñoz; Annemieke Verstuyf


Book ID
116698426
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
252 KB
Volume
121
Category
Article
ISSN
0960-0760

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## Abstract The ligand‐based three‐dimensional quantitative structure‐activity relationship (3D‐QSAR) for 82 inhibitors of 25‐dehydro‐1__α__‐hydroxyvitamin D~3~‐26,23‐lactone analogs has been studied by using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices