✦ LIBER ✦

CCR5 Antagonists: 3-(Pyrrolidin-1-yl)propionic Acid Analogues with Potent Anti-HIV Activity

✍ Scribed by Lynch, Christopher L.; Hale, Jeffrey J.; Budhu, Richard J.; Gentry, Amy L.; Finke, Paul E.; Caldwell, Charles G.; Mills, Sander G.; MacCoss, Malcolm; Shen, Dong-Ming; Chapman, Kevin T.; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Cascieri, Margaret A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Emini, Emilio

Book ID: 121361696
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 62 KB
Volume: 5
Category: Article
ISSN: 1523-7060
DOI: 10.1021/ol034707c

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A Small-Molecule, Nonpeptide CCR5 Antago

A Small-Molecule, Nonpeptide CCR5 Antagonist with Highly Potent and Selective Anti-HIV-1 Activity

✍ Masanori Baba, Osamu Nishimura, Naoyuki Kanzaki, Mika Okamoto, Hidekazu Sawada, 📂 Article 📅 1999 🏛 National Academy of Sciences 🌐 English ⚖ 956 KB

ChemInform Abstract: 1,3,4-Trisubstitute

ChemInform Abstract: 1,3,4-Trisubstituted Pyrrolidine CCR5 Receptor Antagonists. Part 2. Lead Optimization Affording Selective, Orally Bioavailable Compounds with Potent anti-HIV Activity.

✍ Jeffrey J. Hale; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

1,3,4-Trisubstituted pyrrolidine CCR5 re

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 4: Synthesis of N-1 acidic functionality affording analogues with enhanced antiviral activity against HIV

✍ Christopher L Lynch; Jeffrey J Hale; Richard J Budhu; Amy L Gentry; Sander G Mil 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 119 KB

1,3,4-Trisubstituted Pyrrolidine CCR5 Re

1,3,4-Trisubstituted Pyrrolidine CCR5 Receptor Antagonists. Part 4. Synthesis of N-1 Acidic Functionality Affording Analogues with Enhanced Antiviral Activity Against HIV.

✍ Christopher L. Lynch; et al. et al. 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 78 KB

1,3,4-Trisubstituted Pyrrolidine CCR5 Re

1,3,4-Trisubstituted Pyrrolidine CCR5 Receptor Antagonists. Part 3. Polar Functionality and Its Effect on anti-HIV-1 Activity.

✍ Jeffrey J. Hale; et al. et al. 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 137 KB 👁 1 views

Discovery of a Piperidine-4-carboxamide

Discovery of a Piperidine-4-carboxamide CCR5 Antagonist (TAK-220) with Highly Potent Anti-HIV-1 Activity

✍ Imamura, Shinichi; Ichikawa, Takashi; Nishikawa, Youichi; Kanzaki, Naoyuki; Taka 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 207 KB