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CCR1 knockdown suppresses human non-small cell lung cancer cell invasion

โœ Scribed by Chang-Li Wang; Bing-Sheng Sun; Yong Tang; Hong-Qing Zhuang; Wei-Zhi Cao


Book ID
106123975
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
373 KB
Volume
135
Category
Article
ISSN
1432-1335

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## Abstract Expression of the tumor suppressor deleted in liver cancerโ€1 (DLCโ€1) is lost in nonโ€small cell lung (NSCLC) and other human carcinomas, and ectopic DLCโ€1 expression dramatically reduces proliferation and tumorigenicity. DLCโ€1 is a multiโ€domain protein that includes a Rho GTPase activati