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CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes

✍ Scribed by Takashi Nishida; Harumi Kawaki; Ruth M. Baxter; R. Andrea DeYoung; Masaharu Takigawa; Karen M. Lyons

Book ID
107594149
Publisher
Springer Netherlands
Year
2007
Tongue
English
Weight
652 KB
Volume
1
Category
Article
ISSN
1873-9601

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Connective tissue growth factor (CTGF/CC
Connective tissue growth factor (CTGF/CCN2) is a downstream mediator for TGF-β1-induced extracellular matrix production in osteoblasts
✍ J.A. Arnott; E. Nuglozeh; M.C. Rico; I. Arango-Hisijara; P.R. Odgren; F.F. Safad 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 437 KB

## Abstract Connective tissue growth factor (CTGF/CCN2) is a cysteine‐rich, extracellular matrix (ECM) protein that acts as an anabolic growth factor to regulate osteoblast differentiation and function. Recent studies have identified CTGF as a downstream effector of transforming growth factor‐β1 (T