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CCN1 protects cardiac myocytes from oxidative stress via β1 integrin–Akt pathway

✍ Scribed by Yoshinori Yoshida; Kiyonori Togi; Hironobu Matsumae; Yasuhiro Nakashima; Yoji Kojima; Hiromi Yamamoto; Koh Ono; Tomoyuki Nakamura; Toru Kita; Makoto Tanaka

Book ID: 116294446
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 523 KB
Volume: 355
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2007.01.195

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## Background: Beta 1-integrin modulates cellular phenotype by mediating signals from the extracellular matrix (ecm). although overexpression of integrin molecules in hepatocellular carcinoma (hcc) has been reported, the role of overexpressed beta 1-integrin in the disease process of hcc is not ful