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Cationic niosomes composed of spermine-based cationic lipids mediate high gene transfection efficiency

✍ Scribed by Paecharoenchai, Orapan; Niyomtham, Nattisa; Ngawhirunpat, Tanasait; Rojanarata, Theerasak; Yingyongnarongkul, Boon-ek; Opanasopit, Praneet


Book ID
115538274
Publisher
Informa plc
Year
2012
Tongue
English
Weight
974 KB
Volume
20
Category
Article
ISSN
1061-186X

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## Abstract In an effort to enhance the gene‐transfer efficiencies of cationic lipids and to decrease their toxicities, a series of new phosphoramidate lipids with chemical similarity to cell membrane phospholipids was synthesised. These lipids contained various cationic headgroups, such as arginin