Cationic Micelle-catalyzed Ring-Opening Reactions of Aziridines with Thiols in Water

✍ Scribed by Min Yang; Qin Yang; Puqing Chen; Yiyuan Peng

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 71 KB
• Volume: 29
• Category: Article
• ISSN: 0256-7660
• DOI: 10.1002/cjoc.201190112

✦ Synopsis

Abstract

An efficient and practical method is described for the ring‐opening reactions of N‐tosylaziridines with various thiols in water under mild conditions. Various surfactants have been evaluated to optimize the reactions. Under optimal conditions, these reactions gave rise to the corresponding β‐amino sulfides in good to excellent yields.