Cationic lipid–protamine–DNA (LPD) complexes for delivery of antisense c-myc oligonucleotides
✍ Scribed by Monika Junghans; Stefan M. Loitsch; Sebastian C.J. Steiniger; Jörg Kreuter; Andreas Zimmer
- Book ID
- 116437382
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- French
- Weight
- 256 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0939-6411
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Cationic lipid-based gene delivery systems have shown promise in transfecting cells both in vitro and in vivo. However, these systems tend to form aggregates in liquid formulation during storage, which has limited their clinical applications. As a result, lyophilization of these systems has recently
Antisense oligodeoxy-nucleoside phosphorothioates (OPTs) of L-myc were encapsulated into reconstituted influenzavirus-A envelopes (virosomes). The envelopes of the virosomes consisted of a single positively charged (cationic) lipid bilayer. Binding of cationic virosomes to cellular receptors that ar