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Cation Sensing Receptors in Bone: A Novel Paradigm for Regulating Bone Remodeling?

โœ Scribed by L. Darryl Quarles


Book ID
111485989
Publisher
American Society for Bone and Mineral Research
Year
1997
Tongue
English
Weight
51 KB
Volume
12
Category
Article
ISSN
0884-0431

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ATP and UTP at low concentrations strong
โœ Astrid Hoebertz; Siva Mahendran; Geoffrey Burnstock; Timothy R. Arnett ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 167 KB

There is increasing evidence that extracellular nucleotides act on bone cells via multiple P2 receptors. The naturally-occurring ligand ATP is a potent agonist at all receptor subtypes, whereas ADP and UTP only act at specific receptor subtypes. We have reported that the formation and resorptive act