Cation radius effects on the helix-coil transition of DNA. Cryptates and other large cations
β Scribed by Trend, B.L.; Knoll, D.A.; Ueno, M.; Evans, D.F.; Bloomfield, V.A.
- Book ID
- 119409561
- Publisher
- Biophysical Society
- Year
- 1990
- Tongue
- English
- Weight
- 545 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0006-3495
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π SIMILAR VOLUMES
A general theory of polyelectrolyte solutions is here used to calculate the differences in Gibbs free energy, enthalpy, and entropy between the coil and helix forms of DNA a t any temperature and salt concentration. The salt has univalent cations and is assumed present in excess over the base concen
## Synopsis The thermal denaturation method was employed to study the effect of Ca2+ and Mn2+ ions on the DNA helix-coil transition parameters at Na+ concentrations of 10-3-10-1M. A t low ion concentrations, thermal stability increases, the melting range passes through a maximum, and the denaturat
Polyamines are ubiquitous cellular components that interact strongly with nucleic acids. Although many of the interactions of oligocations with DNA can be rationalized with polyelectrolyte theories that treat counterions as point charges, some structural effects are evident. We have explored the eff