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Cathepsin K, Osteoclastic Resorption, and Osteoporosis Therapy

✍ Scribed by Mone Zaidi; Bruce Troen; Baljit S. Moonga; Etsuko Abe

Book ID
111486852
Publisher
American Society for Bone and Mineral Research
Year
2001
Tongue
English
Weight
26 KB
Volume
16
Category
Article
ISSN
0884-0431

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## Abstract The best established proteolytic event of osteoclasts is bone matrix solubilization by the cysteine proteinase cathepsin K. Here, however, we draw the attention on osteoclastic activities depending on matrix metalloproteinases (MMPs). We discuss the observations supporting that MMPs con