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Cathepsin E induces itch-related response through the production of endothelin-1 in mice

✍ Scribed by Tsugunobu Andoh; Tetsuro Yoshida; Jung-Bum Lee; Yasushi Kuraishi


Book ID
113589881
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
401 KB
Volume
686
Category
Article
ISSN
0014-2999

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## Abstract Adenosine, a purine nucleoside, has been reported to suppress the inflammatory responses of microglia in the brain. However, the underlying mechanisms of its anti‐inflammatory action are unclear at present. Here we show that adenosine reduces the increase in intracellular reactive oxyge