Cathepsin D immunoreactivity in ovarian cancer: Correlation with prognostic factors
β Scribed by Pauline Athanassiadou; Vasiliki Sakellariou; Efthalia Petrakakou; Peter Athanassiades; Cherry Zerva; Anna Liossi; Stylianos Michalas
- Publisher
- Springer Netherlands
- Year
- 1998
- Tongue
- English
- Weight
- 645 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1219-4956
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Background. Tetranectin (TN), a tetrameric, plasminogen-binding protein, was reduced in the plasma of patients with cancer and appears extracellularly in "stimulated" connective tissues, such as the proliferative, connective tissue response to carcinomas known as desmoplasia. Methods. Tissue sample
Ki-67 immunoreactivity was studied in relation to immunohistochemically assessed expression of epidermal-growth-factor receptor (EGFR), estrogen receptor (ER) progesterone receptor (PgR) and cytosolic levels of cathepsin D in advanced human ovarian adenocarcinomas, borderline and benign cystadenomas
Sixty-three patients with primary laryngeal squamous-cell carcinoma were followed up for a median of 33 months after surgery. Cathepsin D (Cath D) concentration was assayed using a solid phase 2-site immunoradiometric assay in which the first monoclonal antibody (MAb) was coated on the ELISA solid p