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Cathepsin C Gene Variants in Aggressive Periodontitis

✍ Scribed by Noack, B.; Gorgens, H.; Hempel, U.; Fanghanel, J.; Hoffmann, Th.; Ziegler, A.; Schackert, H.K.

Book ID
121731128
Publisher
International and American Association of Dental Research
Year
2008
Tongue
English
Weight
882 KB
Volume
87
Category
Article
ISSN
0022-0345

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## Communicated by Mark H. Paalman We have previously reported that loss-of-function mutations in the cathepsin C gene (CTSC) result in Papillon-Lefe `vre syndrome, an autosomal recessive condition characterized by palmoplantar keratosis and early-onset, severe periodontitis. Others have also repo