Cathepsin B and other proteases in human articular cartilage
โ Scribed by S.Yousuf Ali; Michael T. Bayliss
- Book ID
- 113214083
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 327 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0049-0172
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๐ SIMILAR VOLUMES
## Abstract The aim of this study was to determine the involvement of cathepsin B and its inhibitors in the proteolytic degradation of human osteoarthritic (OA) tissue. The characteristics of the cathepsin B found in both normal and OA cartilage and synovium were similar to those of the lysosomal c
Proteases have been postulated to account for the progressive disappearance of matrix proteoglycans in osteoarthritic (OA) cartilage. The digestion of endogenous proteoglycans by neutral proteases in human OA cartilage homogenates has been measured and compared with that of normal age-matched contro