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Catharanthus alkaloids XXVI: Isolation of cathanneine, a new alkaloid from Catharanthus lanceus

✍ Scribed by G. Aynilian; N. R. Farnsworth; R. L. Lyon; H. H. S. Fong


Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
123 KB
Volume
61
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES


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rnl d "0 OIW M \* d 0 20 w 60 an im 120 1. 0 M 180 M(I 2m lYlt4JTESl Fig. 1.-Acid consuming activity of four metal comnlexes of THAM. Kev: A. aluminum-eluconic Journal of Pharmaceutical Sciences Fn mI d K I WN . O M 8 0 o m w UI m im tm I.O ICO ,a I----L-L-'""""' " " " ' --

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## Abstract 17‐desacetoxyvinblastine and 17‐desacetoxyleurosine have been isolated from Catharanthus roseus. The latter has not been recognized so far in this plant. The ^1^H NMR and mass spectrometry data confirming the proposed structures are presented.

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Certain active cytotoxic alkaloid fractions prepared from Catharanthus trichophyllus roots were investigated. This work resulted in the isolation of ajmalicine, pericalline, tetrahydroalstonine, vindolinine, and ursolic acid. These compounds were not responsible for the observed cytotoxic activity.