## Background: The 5-year survival rate of patients with submucosal (sm) esophageal carcinoma continues to be much worse than that with intramucosal (m) lesions. the reasons are unclear, but matrix metalloproteinases (mmps) and membrane type matrix metalloproteinases (mt-mmps) are known to be invol
CATECHOLAMINES SYNERGISTICALLY INCREASE LIPOPOLYSACCHARIDE-INDUCED EXPRESSION OF MATRIX METALLOPROTEINASE-1 AND MATRIX METALLOPROTEINASE-9 IN HUMAN MONOCYTES
โ Scribed by Walter S Speidl; Wolfgang G Toller; Christoph Kaun; Thomas W Weiss; Helfried Metzler; Kurt Huber; Johann Wojta
- Book ID
- 116342303
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 42 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1054-8807
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## Abstract Matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) play major roles in physiological extracellular matrix turnover during normal development and in pathological processes. In brain, increases in MMP activity occur, for example, in multiple sclero
Neuroinflammatory diseases are associated with increased production of matrix metalloproteinase-9 (MMP-9) and excessive generation of nitric oxide (NO). NO has been reported to have variable effects on MMP-9 gene expression and activation in various cell types. In the present study, we investigated