Oxidative demethylenation and subsequent
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Yitong Liu; Haiping Hao; Hongguang Xie; Hua Lv; Changxiao Liu; Guangji Wang
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Article
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2009
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John Wiley and Sons
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English
โ 151 KB
Present study was designed to explore roles of metabolic clearance in the disposition of berberine (BBR) in rats, with a focus on oxidative metabolism and subsequent glucuronidation. Plasma from rats after intravenous administration of BBR was collected to identify and quantify BBR and its major met