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Catechol-O-methyltransferase low activity genotype (COMTLL) is associated with low levels of COMT protein in human hepatocytes

✍ Scribed by Anne E. Sullivan Doyle; Julie E. Goodman; Paul M. Silber; James D. Yager

Book ID
116333234
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
117 KB
Volume
214
Category
Article
ISSN
0304-3835

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## Abstract The catechol‐__O__‐methyltransferase (__COMT__) gene is considered as a candidate gene in obsessive–compulsive disorder (OCD). Specifically, the __COMT__ low‐activity M158 allele has been suggested to be associated with OCD. However, there is no study reporting that COMT activity is dec