Catbarantbus alkaloids XV. Isolation of vindolinine from C. lanceus leaves
✍ Scribed by Edward M. Maloney; Harry H. S. Fong; Norman R. Farnsworth; Ralph N. Blomster; Donald J. Abraham
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- English
- Weight
- 270 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
✦ Synopsis
A continuing study of Catbarantbus lanceus for antineoplastic alkaloids has resulted in the isolation of vindolinine (as HCI), which is reported for the first time from this plant. Perivine and yohirnbine, reported previously, were also obtained in high yield.
N A PREVIOUS communication (1) the isolation of I perivine and yohimbine from the (B) fraction of C. lanceus leaves was reported. A reinvestigation of this fraction has resulted in the isolation of vindolinine, as the dihydrochloride salt. This is the first report on the isolation of vindolinine from C. lunreus, however it was initially isolated from the related C. roseus by two other groups (2,3).