Catalyzed reactions of α-amino diazoketones with allyl sulfides: a new synthetic protocol for α-amino homoallyl ketones en route to 3-piperidinol alkaloids

✍ Scribed by Saumitra Sengupta; Somnath Mondal

• Publisher: Elsevier Science
• Year: 2000
• Tongue: French
• Weight: 148 KB
• Volume: 41
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)00282-3

✦ Synopsis

Cu(acac) 2 -catalyzed reactions of enantiopure α-amino diazoketones with allyl sulfides provide a facile synthetic route to α-amino homoallyl ketones via 2,3-sigmatropic rearrangements of the derived allyl sulfonium ylides.