Catalyzed double Michael addition of anilines to vinyl sulfone

✍ Scribed by Jiong Jack Chen; Cuong V. Lu; Rebecca N. Brockman

• Book ID: 104253491
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 131 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)00702-0

✦ Synopsis

Substituted anilines and vinyl sulfone undergo a facile double Michael addition to form substituted phenylthiomorpholine dioxide, catalyzed with AlCl 3 or H 3 PO 4 . Scope and conditions were explored.