✦ LIBER ✦

Catalytic Reaction of Aryldiazoacetates with Indole and Its Derivatives:Profound Effect of N-1 Substitutent on the Reaction Pathways

✍ Scribed by Xue-Jing ZHANG; Sheng-Ping LIU; Ming YAN

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 97 KB
Volume: 26
Category: Article
ISSN: 0256-7660
DOI: 10.1002/cjoc.200890134

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The reaction of indole and its derivatives with aryldiazoacetates has been studied in the presence of copper and rhodium catalysts. The electronic property of N‐1 substitutent showed significant effect on the reaction pathways. The electron‐donating group favored the formation of the β‐alkylation products, while the electron‐withdrawing group favored the formation of the cyclopropane products. A reaction mechanism was proposed based on the experimental data and previous research results. The structure of aryl group in diazo compounds also affected the yield of the β‐alkylation products or the cyclopropane products.

📜 SIMILAR VOLUMES

ChemInform Abstract: Catalytic Reaction

ChemInform Abstract: Catalytic Reaction of Aryldiazoacetates with Indole and Its Derivatives: Profound Effect of N-1 Substitutent on the Reaction Pathways.

✍ Xue-Jing Zhang; Sheng-Ping Liu; Ming Yan 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

The Profound Effect of Fluorine Substitu

The Profound Effect of Fluorine Substitution on the Reactivity and Regioselectivity of Nucleophilic Substitution Reactions of Strained Heterocycles. A Study of Aziridine and Its Derivatives.

✍ Harold D. Banks 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 8 KB 👁 2 views

ChemInform Abstract: Reaction of Anthron

ChemInform Abstract: Reaction of Anthrone and Its 1- and 4-Substituted Derivatives with Sulfur in the Presence of Nucleophiles.

✍ V. A. Loskutov 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Catalytic Determination of Trace Amounts

Catalytic Determination of Trace Amounts of Tellurium(IV) Based on Its Catalytic Effect in the Reduction Reaction of Bromate with Hydrazinium Dichloride

✍ A. Safavi; A. Afkhami; A. Massoumi 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 255 KB

The Effect of Coordination on the Reacti

The Effect of Coordination on the Reaction of N-Tosyl Imines with Diethylzinc.

✍ Feifeng Gao; Minzhi Deng; Changtao Qian 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

Fluorimetric Kinetic-FIA Determination o

Fluorimetric Kinetic-FIA Determination of Ag(I) Based on Its Catalytic Effect on the Reduction Reaction of Safranine with Iodide

✍ A. Safavi; M.R. Baezzat 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 93 KB

A sensitive kinetic fluorimetric flow injection method has been developed for the determination of Ag(I) over the range 100-2500 ng. The method is based on the catalytic effect of Ag(I) on the reduction reaction of safranine by iodide. Method development includes optimization of reagent concentratio