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Catalytic Preparation of Aziridines with an Iron Lewis Acid

✍ Scribed by Mayer, Michael F.; Hossain, M. Mahmun


Book ID
111688949
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
94 KB
Volume
63
Category
Article
ISSN
0022-3263

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Treatment of trifluoroacetaldehyde N,O-acetal with diazoacetate in the presence of a Lewis acid furnished CF 3 -substituted aziridinecarboxylates in good yields. Both cis and trans isomers were obtained stereoselectively by the proper choice of the ester substituents. Use of a chiral diazoacetate de