Catalytic Oxidation of Imines Based on Methyltrioxorhenium/Urea Hydrogen Peroxide: A Mild and Easy Chemo- and Regioselective Entry to Nitrones

✍ Scribed by Soldaini, Gianluca; Cardona, Francesca; Goti, Andrea

• Book ID: 120344973
• Publisher: American Chemical Society
• Year: 2007
• Tongue: English
• Weight: 64 KB
• Volume: 9
• Category: Article
• ISSN: 1523-7060
• DOI: 10.1021/ol062862w

✦ Synopsis

The first successful catalytic oxidation procedure for the chemoselective conversion of imines to nitrones is reported. The reaction is general, high yielding, and user and environmentally friendly, and furnishes a solution to the yet unanswered issue of regioselective access to nitrones by oxidation of nitrogen derivatives.