Catalytic Ionic Hydrogenations

✍ Scribed by R. Morris Bullock

• Book ID: 101836301
• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 261 KB
• Volume: 10
• Category: Article
• ISSN: 0947-6539
• DOI: 10.1002/chem.200305639

✦ Synopsis

Abstract

Catalytic ionic hydrogenation of ketones occurs by proton transfer to a ketone from a cationic metal dihydride, followed by hydride transfer from a neutral metal hydride. This contrasts with traditional catalysts for ketone hydrogenation that require binding of the ketone to the metal and subsequent insertion of the ketone into a MH bond. Ionic hydrogenation catalysts based on the inexpensive metals molybdenum and tungsten have been developed based on mechanistic understanding of the individual steps required in the catalytic reaction.