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Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress

✍ Scribed by Qing S. Lin; Sebastian Weis; Guang Yang; Tiangang Zhuang; Aida Abate; Phyllis A. Dennery

Book ID: 113630501
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 925 KB
Volume: 44
Category: Article
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2007.11.012

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## Abstract Heme oxygenase‐1 (HO‐1) is known as a stress‐inducible protein and functions as an antioxidant enzyme. It has been shown that HO‐1 is induced rapidly by a variety of chemical and physical stimuli. However, little is known about the induction of cellular signaling events after cell expos