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Catalytic Fluorimetric Determination of Trace Cobalt in Vitamin B12

✍ Scribed by Guien Zhang; Suling Feng; Dingxi Cheng


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
86 KB
Volume
53
Category
Article
ISSN
0026-265X

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✦ Synopsis


A new kinetic fluorimetric method is proposed for the determination of trace cobalt, based on the catalytic oxidation of reduced fluoresceine with hydrogen peroxide in the presence of triethanolamine as activator in a basic medium. The detection limit for cobalt is 0.016 ng/ml and the linear range of the determination is 0.08-1.40 ng/ml. The application of this method to the determination of trace cobalt in vitamin B 12 samples shows satisfactory results.


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