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Catalytic Enantioselective Fluorination of Oxindoles.

โœ Scribed by Yoshitaka Hamashima; Toshiaki Suzuki; Hisashi Takano; Yuta Shimura; Mikiko Sodeoka

Publisher
John Wiley and Sons
Year
2005
Weight
37 KB
Volume
36
Category
Article
ISSN
0931-7597

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The Mechanism of Catalytic Enantioselect
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Despite the undisputed importance of organofluorine compounds, for example, in biomedical applications, the generation of fluorinated carbon stereocenters by Cร€F bond-forming reactions remains rare and particularly challenging. [1, 2] Recently, the first catalytic, enantioselective fluorination of b