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Catalytic enantioselective direct Michael additions of ketones to alkylidene malonates

โœ Scribed by Juan M Betancort; Kandasamy Sakthivel; Rajeswari Thayumanavan; Carlos F Barbas III

Book ID
104230858
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
61 KB
Volume
42
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Enantioselective direct Michael additions of ketones using (S)-1-(2-pyrrolidinylmethyl)-pyrrolidine as a catalyst are described. Michael adducts with up to 91% e.e. were obtained by the reaction of alkylidene malonates with simple unactivated ketones under mild reaction conditions.

๐Ÿ“œ SIMILAR VOLUMES

Enantioselectively Organocatalytic Micha
Enantioselectively Organocatalytic Michael Addition of Ketones to Alkylidene Malonates.
โœ Chun-Li Cao; Xiu-Li Sun; Jiao-Long Zhou; Yong Tang ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons โš– 29 KB ๐Ÿ‘ 2 views

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