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Catalytic Enantioselective Dibromination of Allylic Alcohols

โœ Scribed by Hu, Dennis X.; Shibuya, Grant M.; Burns, Noah Z.


Book ID
120826559
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
544 KB
Volume
135
Category
Article
ISSN
0002-7863

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Catalytic enantioselective cyclopropanat
โœ Tsuyoshi Miura; Keisuke Itoh; Yumi Yasaku; Naka Koyata; Yasuoki Murakami; Nobuyu ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 162 KB

Cyclopropanation of allylic alcohols with Et 2 Zn and CH 2 I 2 in the presence of a catalytic amount of fluorous disulfonamide 3 afforded the corresponding cyclopropylmethanols in 69-96% yield with 49-83% ee. The fluorous ligand 3 was readily recovered from the reaction mixture by the fluorous solid