Catalytic Enantioselective Aza-Henry Reaction with Broad Substrate Scope.
✍ Scribed by Claudio Palomo; Mikel Oiarbide; Antonio Laso; Rosa Lopez
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 33 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract magnified image A highly enantioselective aza‐Henry reaction of imines with nitromethane was achieved with a reactive guanidine‐thiourea bifunctional organocatalyst affording β‐nitroamines with high enantioselectivity (up to 96% __ee__). The diastereo‐ and enantioselective version of t
## Abstract The syntheses of enantiomer‐enriched orthogonally protected different (2__S__)‐2,3‐diaminopropanoates and unnatural furyl‐substituted (__tert__‐butoxy)carbonyl (Boc) as well as (benzyloxy)carbonyl (Cbz) protected amino acid esters are accomplished by means of an enantioselective aza‐__H