✦ LIBER ✦
Catalytic durability of magnetoproteoliposomes captured by high-gradient magnetic forces in a miniature fixed-bed reactor
✍ Scribed by Marcel De Cuyper; Bruno De Meulenaer; Pol Van der Meeren; Jan Vanderdeelen
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 541 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0006-3592
No coin nor oath required. For personal study only.
✦ Synopsis
Cytochrome c-oxidase, used as a model membranebound enzyme, was embedded in phospholipid bilayer membranes, attached to nanometer-sized Fe,O, colloids (so-called magnetoliposomes). In comparison with the lipid-depleted free enzyme, both the activity and the enzymatic stability of the complexes, stored at 4"C, were considerably enhanced. These beneficial properties of magnetoproteoliposomes have been successfully exploited in a magnetically controlled fixed-bed bioreactor, operating in a continuous flow regime. 0 1996