Catalytic decomposition of alkyl chloroformates by hexabutylguanidinium chloride

✍ Scribed by Frédérique Foulon; Bernard Fixari; Dominique Picq; Pierre Le Perchec

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 162 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)00626-6

✦ Synopsis

Hexabutylguanidinium chloride (0.5 molar %) efficiently decomposes alkyl chloroformates into chlorides, with low alkenes formation, via a S~2 mechanism as demonstrated from substituents effects and asymmetric chloride .wnthesis, © 1997 Elsevier Science Ltd.

Surfactants, drugs and herbicides are produced from alkyl halides, starting from haloformates.1, 2 Furthermore, recent patents2, 3 and publications4, 5 on syntheses of alkyl halides have appeared, with a particular interest focused on synthesis of optically active products. This prompt us to study in more details