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Catalytic Asymmetric Oxidation of Aryl Sulfides with a Ti/H 2 O/( R,R )-Diphenylethane-1,2-diol Complex: a Versatile and Highly Enantioselective Oxidation Protocol

โœ Scribed by Donnoli, Maria Irene; Superchi, Stefano; Rosini, Carlo


Book ID
120291475
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
53 KB
Volume
63
Category
Article
ISSN
0022-3263

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Catalytic asymmetric oxidation of aryl m
โœ Stefano Superchi; Carlo Rosini ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 238 KB

The asymmetric oxidation of aryl methyl sulfides to sulfoxides with hydroperoxides has been achieved using catalytic amounts of the complex formed in situ between Ti(i-PrO) 4, (S,S)-diphenylethan-l,2-diol 1 and water. The sulfoxides are obtained in 60% yield and 67-80% enantiomeric excess.