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Catalytic and Asymmetric Vinylogous Mukaiyama Reactions on Aliphatic Ketones: Formal Asymmetric Synthesis of Taurospongin A.

✍ Scribed by Xavier Moreau; Belen Bazan-Tejeda; Jean-Marc Campagne


Publisher
John Wiley and Sons
Year
2005
Weight
35 KB
Volume
36
Category
Article
ISSN
0931-7597

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The syntheses were carried out under argon with use of Schlenk techniques and predried solvents. Cyclopentadiene (ca. 5 mL, ca. 75 mmol) was added dropwise to metallic cesium (5.90 g. 42.1 mmolj in T H F (90 mL). The blue color of the solvated electrons disappeared and the solution was slowly warmed