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Catalytic Activity of Protein Kinase CK1δ (Casein Kinase 1δ) Is Essential for Its Normal Subcellular Localization

✍ Scribed by Diane M. Milne; Paul Looby; David W. Meek

Book ID
115603891
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
385 KB
Volume
263
Category
Article
ISSN
0014-4827

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## Abstract **Background:** Cell lines that stably over‐express protein kinase C (PKC) δ frequently show a decrease in growth rate and saturation density, leading to the hypothesis that PKCδ has a negative effect on cell proliferation. However, the mode of PKCδ activation, the cell cycle stage requ