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Catalyst-Free, Efficient, and Facile Conversion of Epoxides to β-Hydroxy Thiocyanates Under Neutral Conditions

✍ Scribed by Aghapour, Ghasem; Hatefipour, Razieh


Book ID
120803399
Publisher
Taylor and Francis Group
Year
2009
Tongue
English
Weight
211 KB
Volume
39
Category
Article
ISSN
0039-7911

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Facile conversion of epoxides to β-hydro
✍ James A. Ciaccio; Catherine Stanescu; Jongnic Bontemps 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 236 KB

Functionalir@d epoxides are easily and efficiently converted lo P-hydroxy nitnles In good yield with high fegio-and stereoselectivity upon treatment with lithium cyanide in rcfluxing anhydrous THF The conditions described permit a one-pot conversion of epoxide to 1 J-amino alcohol via hydnde reducti