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Catalyst- and Pressure-Dependent Reductive Cyclizations for the Diastereoselective Synthesis of Hexahydropyrrolo[1,2-a]quinoline-5-carboxylic Esters.

✍ Scribed by Richard A. Bunce; James E. Schammerhorn; LeGrande M. Slaughter


Publisher
John Wiley and Sons
Year
2007
Weight
24 KB
Volume
38
Category
Article
ISSN
0931-7597

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Catalyst and pressure dependent reductiv
✍ Richard A. Bunce; James E. Schammerhorn; Legrande M. Slaughter 📂 Article 📅 2006 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 505 KB

## Abstract magnified image A diastereoselective synthesis of 1,2,3,3a,4,5‐hexahydropyrrolo[1,2‐__a__]quinoline‐5‐carboxylic esters has been developed using a tandem reduction‐double reductive amination reaction. The nitro dicarbonyl cyclization substrates were synthesized by alkylation of methyl