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Catalysis by mutants of human carbonic anhydrase II: effects of replacing hydrophobic residues 198 and 204

✍ Scribed by Shinichi Taoka; Xian Chen; Roy W. Tarnuzzer; Gino Van Heeke; Chingkuang Tu; David N. Silverman


Book ID
113268710
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
459 KB
Volume
1159
Category
Article
ISSN
0167-4838

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The development of commercial biosensors based on surface plasmon resonance has made possible careful characterization of biomolecular interactions. Here, a set of destabilized human carbonic anhydrase II (HCA II) mutants was investigated with respect to their interaction kinetics with two different