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Catalysis by modified polyethylenimine of nucleophilic substitution reactions of azide ions

✍ Scribed by Junghun Suh; Irving M. Klotz

Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
795 KB
Volume
6
Category
Article
ISSN
0045-2068

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Heteroaromatic Nucleophilic Substitution
Heteroaromatic Nucleophilic Substitution Reactions by Phase-Transfer Catalysis– Synthesis of New Alkoxypridazin-3(2H)-ones
✍ Gómez-Gil, M. Carmen ;Gómez-Parra, Vicente ;Sánchez, Félix ;Torres, TomáS 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 528 KB

## Abstract The synthesis of several 4‐ and 5‐alkoxy‐substituted pyridazin‐3(2__H__)‐ones with hypotensive and β‐blocking activities by phase‐transfer catalysis (PTC) starting from halopyridazin‐3(2__H__)‐ones is described. The nucleophilic displacement reaction proceeds easily at the 5‐position an