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Catabolite repression of SOS-dependent and SOS-independent spontaneous mutagenesis in stationary-phase Escherichia coli

โœ Scribed by D.G. MacPhee; M. Ambrose


Book ID
113809433
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
420 KB
Volume
686
Category
Article
ISSN
0027-5107

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The E. coli dnaQ gene encodes the epsilon subunit of DNA polymerase III (pol III) responsible for the proofreading activity of this polymerase. The mutD5 mutant of dnaQ chronically expresses the SOS response and exhibits a mutator phenotype. In this study we have constructed a set of E. coli AB1157