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Catabolic repression and microbial modelling for the yeast Saccharomyces cerevisiae

✍ Scribed by T. V. Subramanian

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
124 KB
Volume
13
Category
Article
ISSN
0138-4988

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✦ Synopsis

The mechanism of catabolic repression is not yet fully understood. Oxygen seems to control the level of cytochrome in the in situ state. The level of glucose seems to control other enzymes; glucose by itself does not repress the catabolism. An unidentified product of glucose metabolism is believed to be involved. In bacterial cultures, there is convincing evidence that cyclic AMP is involved and this operates at the level of gene transcription. In yeast, it is not clear. The level of CAMP is found to be reduced with catabolic repressed cells, but there is little evidence to conclude that CAMP acts at the transcription level [l]. There are results to indicate that it acts at the translational level or enzyme activation phase in yeast. In order to understand this mechanism, the bioenergetics of yeasts grown under catabolic repression is analyzed with the data available [2] and appended.

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