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Castration increases [125I]MK801 binding in the hippocampus of male rats

โœ Scribed by Laura Kus; Robert J. Handa; Joan M. Hautman; Alvin J. Beitz

Book ID
113127516
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
482 KB
Volume
683
Category
Article
ISSN
0006-8993

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The effects of MK-801, a noncompetitive NMDA receptor antagonist, on in vivo and in vitro binding of radioactive iodine ([ 123 I] or [ 125 I]) labeled โค-CIT [RTI-55, 3โค-(4-iodophenyl)tropane-2โค-carboxylic acid methyl ester] were investigated in rat brain. In the in vitro binding study, 10 pM of [ 12