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Castleman disease with renal amyloidosis: imaging findings and clinical significance

✍ Scribed by W. K. Moon; S. H. Kim; J.-G. Im; K. M. Yeon; M. C. Han

Publisher
Springer
Year
1995
Tongue
English
Weight
717 KB
Volume
20
Category
Article
ISSN
0942-8925

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✦ Synopsis

We report two cases of renal amyloidosis associated with mesentefic and mediastinal Castleman disease of plasma cell type. Computed tomographic (CT) scan revealed a mesenteric mass with multiple nodal enlargement in one patient and a fight paratracheal mass with irregular central calcifications in the second patient. Renal ultrasonography (US) showed increased echogenicity of the renal parenchyma with prominent medullas: Doppler waveform obtained in the kidney associated with mesentefic disease showed complete absence of diastolic flow signal, although it was normal in the patient with mediastinal disease. Recognition of Castleman disease as the cause of renal amyloidosis and the understanding of CT and US findings of this entity are important for the management, as well as its diagnosis.

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## Abstract ## Purpose. To correlate the clinical and laboratory findings with increased renal cortical echogenicity in children with acute renal diseases. ## Materials and Methods. Children with increased renal cortical echogenicity were evaluated retrospectively. Laboratory findings and final