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Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells

✍ Scribed by Salmaan H. Inayat-Hussain; Annuar B. Osman; Laily B. Din; Abdul M. Ali; Roger T. Snowden; Marion MacFarlane; Kelvin Cain


Book ID
117111249
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
202 KB
Volume
456
Category
Article
ISSN
0014-5793

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## Abstract Cepharanthine (CEP) is a known membrane stabilizer that has been widely used in Japan for the treatment of several disorders such as anticancer therapy‐provoked leukopenia. We here report that apoptosis was induced by low concentrations (1–5 ΞΌM) of CEP in a human leukemia T cell line, J