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Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing

✍ Scribed by Go Tomiyoshi; Yuji Horita; Michiru Nishita; Kazumasa Ohashi; Kensaku Mizuno

Book ID
108589781
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
301 KB
Volume
9
Category
Article
ISSN
1356-9597

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## Abstract Nitric oxide (NO) can regulate chondrocyte activities. This study was aimed to evaluate the molecular mechanisms of NO donor sodium nitroprusside (SNP)‐induced insults to human chondrocytes. Exposure of human chondrocytes to SNP increased cellular NO levels but decreased cell viability